The Mumbai Indians (MI) defeated the Chennai Super Kings (CSK) in the fifty-ninth game of the 2022 Indian Premier League (IPL). The match was played in the Wankhede Stadium in Mumbai. Daniel Sams was adjudged to be the Man of the Match.
| CHENNAI SUPER KINGS | 97 (16 OVERS) |
| MS DHONI 36* (33) | DANIEL SAMS 4-0-16-3 |
| DWAYNE BRAVO 12 (15) | KUMAR KARTIKEYA 3-0-22-2 |
| SHIVAM DUBE 10 (9) | RILEY MEREDITH 3-0-27-2 |
| AMBATI RAYUDU 10 (14) | RAMANDEEP SINGH 1-0-5-1 |
| MUMBAI INDIANS | 103/5 (14.5 OVERS) |
| TILAK VARMA 34* (32) | MUKESH CHOUDHARY 4-0-23-3 |
| ROHIT SHARMA 18 (14) | MOEEN ALI 1.5-0-17-1 |
| HRITHIK SHOKEEN 18 (23) | SIMARJEET SINGH 4-0-22-1 |
| TIM DAVID 16* (7) | DWAYNE BRAVO 2-0-16-0 |